Lets use the example of a person with trust issues to illustrate the Twelve Nidanas of dependent origination.
1. Ignorance (avijja): The person lacks understanding of the true nature of reality, including the impermanence and non-self nature of all phenomena.
2. Mental formations (sankhara): Due to ignorance, the person forms habitual patterns of being suspicious and distrusting of others.
3. Consciousness (viññana): The persons consciousness is conditioned by these mental formations, making them prone to experiencing mistrust.
4. Name and form (nama-rupa): The persons body and mind (psychophysical constituents) manifest in a way that is sensitive to feelings of mistrust.
5. The six sense bases (salayatana): The persons sense organs (sight, hearing, smell, taste, touch, and mind) interact with the external world.
6. Contact (phassa): The person encounters a situation or stimulus (e.g., someone betraying their trust) that triggers feelings of mistrust.
7. Feeling (vedana): The person experiences an unpleasant feeling as a result of the contact with the situation or stimulus.
8. Craving (tanha): The person develops a desire to avoid situations or people that may trigger feelings of mistrust and to find ways to protect themselves.
9. Clinging (upadana): The persons attachment to their mistrust intensifies and they cling to their defensive behavior as a way of dealing with people and situations.
10. Becoming (bhava): The persons attachment to their mistrust reinforces their habitual patterns and karmic tendencies, leading to more mistrust and negative consequences in future situations.
11. Birth (jati): The persons mistrust manifests in the form of distancing themselves from others and feeling isolated, which reinforces the cycle of mental formations and karmic consequences.
12. Old age and death (jara-marana): The persons mistrust, if left unaddressed, can lead to physical, mental, and emotional suffering and perpetuate negative consequences in future situations or even future lives.
This example illustrates how the Twelve Nidanas apply to the arising and perpetuation of trust issues. By understanding the dependent origination of mistrust and recognizing the interdependence of the Twelve Links, a person can cultivate self-awareness and work towards breaking the cycle of mistrust, leading to greater trust, connection, and freedom from suffering.

How to break cycle at each point:

To break the cycle of dependent origination in the case of trust issues, an individual can focus on different points in the chain, each leading to a reduction in suffering:

1. Ignorance (avijja): The person can work on developing wisdom and understanding of the impermanent and interconnected nature of reality. By recognizing that all things are constantly changing, that people are inherently interdependent, and that situations are not fixed, the person can challenge their fixed views and beliefs that support their mistrust.

2. Mental formations (sankhara): The person can cultivate wholesome mental states such as loving-kindness, compassion, and generosity, which will reinforce positive patterns of thinking and behavior. By practicing empathy and kindness towards others, the person can work towards dismantling their habitual patterns of mistrust.

3. Consciousness (viññana): Through mindfulness practice, the person can become aware of the ways in which their mistrust shapes their experience of situations and relationships. They can learn to observe their thoughts and reactions without judgment or reactivity.

4. Name and form (nama-rupa): By developing greater self-awareness and understanding of their own bodily and mental patterns, the person can recognize the physical and mental sensations associated with mistrust. By attending to these sensations with a non-judgmental attitude, they can reduce their impact on their behavior and decision-making.

5. The six sense bases (salayatana): The person can practice mindfulness and restraint when encountering triggers or situational stimuli that trigger their mistrust. By recognizing their own reactive patterns, they can practice self-control and focus on positive, supportive reactions.

6. Contact (phassa): By developing greater awareness of their emotional triggers and situations that lead to mistrust, the person can work to avoid or mitigate these situations. They can also practice mindfulness when experiencing these triggers, allowing them to observe and accept uncomfortable emotions without reacting.

7. Feeling (vedana): The person can work on developing greater emotional resilience, accepting that difficult emotions such as sadness, anger, and hurt are inevitable. By observing and accepting these feelings without judgment or resistance, the person can begin to loosen the grip of craving and clinging.

8. Craving (tanha): The person can work on developing equanimity, recognizing that all things are subject to change and that nothing is permanent. By focusing on the present moment and accepting that not all things can be controlled, the person can reduce their attachment to outcomes and feelings.

9. Clinging (upadana): The person can work on developing self-compassion, recognizing that their mistrust is a result of past experiences and habits of thought. By viewing themselves with kindness and acceptance, the person can reduce their attachment to their mistrust habits and begin to dismantle them.

10. Becoming (bhava): By practicing self-compassion, mindfulness, and equanimity, the person can begin to disrupt karmic tendencies and patterns, reducing the likelihood of future mistrust and negativity.

11. Birth (jati): The person can work on developing positive relationships with others, practicing empathy, kindness, and understanding. By cultivating a network of stable relationships, the person can reduce their sense of isolation and promote positive mental states.

12. Old age and death (jara-marana): By working to break the cycle of mistrust through mindfulness and self-awareness, the person can promote greater overall well-being, happiness, and freedom from negative mental states.